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The appearance of nails changes. Indicates whether it is a dermatological-related condition like psoriasis, lichen planus, eczema, or other systemic associated diseases such as anemia, cardiovascular disease, malnutrition, etc. 

The nail can be infected by fungi and bacteria, cause nail discolouration, increase in thickness of the nail, or may become deformed.  

Apart from that, there could be a possible chance of acquiring cancer that affects the nails, such as nail melanoma and squamous cell carcinoma. 

Few examples area


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Topical corticosteroid
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Topical calcineurin inhibitor
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Biologic such as Baricitinib