Is Rejuran painful? Are All Skin Booster Injections Painful? How Dermashine Pro May Improve Comfort During Your Treatment Session

“I love the effect of Rejuran for my face but its so painful”

“Dr, I need stronger and longer numb cream before my Rejuran skinbooster today”

“How long does the bumps last after my skin booster today? Can I go to Gym after this?’”

These are the common things I hear daily at my skin clinic whenever a patient comes in for a consult on Skin Boosters. Whether its Rejuran, Plenhyage or Plinest, most of them are concerned of two things, PAIN and DOWNTIME.

Skin boosters can improve skin hydration, texture, elasticity and fine lines, but many patients hesitate because they are worried about pain and downtime.

– Downtime refers to the recovery period after an aesthetic treatment when temporary redness, swelling, bruising, peeling or injection bumps may still be visible.

The truth is that skin-booster injections are not completely painless. However, discomfort may be reduced through appropriate numbing, careful product selection and a suitable injection technique such as injection technique that creates less trauma such as the 3-point Cannula technique.

At LiV Clinic, selected skin boosters may be administered using Dermashine Pro, an automated, vacuum-assisted multi-needle injection system. It is designed to deliver small, controlled amounts of product at a consistent depth while making full-face treatment more efficient. And most importantly reducing the PAIN and DOWNTIME that usually occurs during skinbooster/injectables treatments.

However, Dermashine Pro is not automatically the best method for every patient, product or treatment area. Doctor first evaluates the patient’s skin concern before deciding whether automated or manual injection is more suitable.

What Is a Skin Booster?

A skin booster is an injectable treatment intended mainly to improve skin quality rather than dramatically change the shape or volume of the face such as Rejuran.

Depending on the product used, skin boosters may be considered for concerns such as:

  • Dehydrated skin
  • Fine superficial lines
  • Crepey skin
  • Reduced elasticity
  • Enlarged pores
  • Uneven skin texture
  • Dull-looking skin
  • Early signs of skin ageing
  • Skin affected by environmental damage
  • Pigmentation

 

Some well known skin boosters currently in the market now are Rejuran, Plenhyage, Plinest, Profhilo, Revok50, Belotero and Re20.

What Is Dermashine Pro?

Dermashine Pro is an automated injection device used to deliver skinboosters and other injectable products into the skin.

It uses vacuum suction + multiple fine needles to hold the skin steady and deliver a controlled amount of product at a selected depth.

This allows for:

  • More even injections
  • Controlled dosing
  • Adjustable injection depth
  • Consistent treatment across larger areas
  • Faster treatment

Important: Dermashine Pro is the injection device, not the skinbooster itself.

Treatment results still depend on:

  • Type of skinbooster used
  • Skin condition
  • Injection depth
  • Amount injected
  • Number of treatment sessions
  • Interval between sessions

Is Dermashine Pro Completely Painless?

No injection device can guarantee that a skin-booster treatment will be completely painless.

Dermashine Pro is designed to create a more controlled and efficient treatment experience. Its fine multi-needle cartridge, automated dosing and vacuum-assisted skin stabilisation may help make the injection process feel more comfortable.

However, the patient may still feel:

  • Suction or pulling
  • Needle pricks
  • Pressure

It is more accurate to describe Dermashine Pro as a comfort-focused, controlled injection technique rather than a completely painless treatment.

Patient comfort still depends on the complete treatment protocol.

Dermashine Pro vs Manual Skin Booster Injection

Feature Dermashine Pro Manual injection
Injection delivery Automated multi-needle delivery Individual injections performed by hand
Injection depth Selected and standardised through device settings Adjusted manually at each injection point
Dose distribution Repeated controlled microdoses Can be individually customised
Treatment pattern Suitable for systematic coverage of broad areas Suitable for precise, targeted placement
Product compatibility Depends on product viscosity and protocol May accommodate a wider range of techniques
Customisation Consistent across broad treatment areas Greater flexibility for individual anatomical areas
Pain Varies between patients Varies according to technique and treatment area
Neither technique is universally superior.

Potential Advantages of Dermashine Pro

  • More consistent injection depth
  • More uniform microdosing
  • Efficient full-face coverage
  • Comfort-focused treatment planning

Can Dermashine Pro Reduce Bruising?

Bruising can sometimes occur with both automated and manual skin-booster injections. It happens when a needle disrupts a small blood vessel beneath the skin.

However, controlled injections using Dermashine significantly reduces the risk of bruising.

Which Products Can Be Used With Dermashine Pro?

Dermashine Pro may be used to deliver selected:

  • Hyaluronic acid-based skin boosters (Revok50,XelaRederm)
  • Mesotherapy solutions
  • Polynucleotide treatments (Rejuran,Plinest,Plenhyage)
  • Other compatible injectable skin-quality products (Juvelook,Re20)

Product choice must follow the product’s instructions, compatibility, local regulatory requirements and the practitioner’s clinical judgement.

When May Manual Injection Be More Suitable?

Manual injection by Doctor may be preferred when:

  • A highly targeted injection pattern is required
  • Different facial areas require different depths
  • The product is relatively viscous
  • Precise placement is needed around delicate anatomy
  • The practitioner wants to avoid a visible blood vessel
  • Only a small treatment area is being treated
  • The product is intended for a specific bolus, linear or cannula technique


The best technique is the one that delivers the selected product safely and appropriately for the patient’s concern.

Who May Benefit From Dermashine Pro Skin Booster Treatment?

Dermashine Pro may be considered for patients who:

  • Are concerned about repeated manual injections
  • Want a controlled full-face treatment pattern
  • Have dehydrated or dull-looking skin
  • Have early fine lines
  • Want to improve general skin texture
  • Prefer a consistent microinjection approach
  • Are suitable for the selected injectable product
  • Understand that some discomfort and downtime remain possible

What Happens During Treatment at LiV Clinic?

What Is the Downtime?

Downtime is possible short-term effects include:

  • Redness
  • Mild swelling
  • Small injection bumps
  • Pinpoint bleeding
  • Bruising
  • Tenderness
  • Temporary itching or sensitivity


Downtime varies according to the product, injection depth, treatment area and individual response. Using Dermashine Pro for your skin booster sessions greatly reduces downtime risks.

Patients should schedule treatment with sufficient recovery time before an important event.

Skin Booster Aftercare

After skin booster treatment, patients may be advised to:

  • Avoid rubbing or massaging the area unless instructed
  • Avoid strenuous exercise temporarily
  • Avoid saunas, steam rooms and excessive heat
  • Avoid alcohol for a short period when appropriate
  • Use gentle skincare
  • Avoid strong exfoliating acids and retinoids temporarily
  • Apply sunscreen
  • Avoid applying unclean makeup tools over fresh injection sites
  • Contact the clinic if unusual pain, persistent blanching, increasing redness or other concerning symptoms develop


Specific aftercare may differ according to the product used.

Frequently Asked Questions

Numbing may still be used depending on the patient, product and treatment area. Dermashine Pro does not eliminate the need for pain-management measures in every patient.

Temporary pinpoint marks, redness or small bumps may still occur. But the risks is very minimal.These generally settle as the skin recovers.

Small amounts of product may occasionally remain on the skin surface following multi-needle injection. The suction mechanism of the Dermashine Pro machine is designed to minimise leakage.The amount can vary according to skin contact, device settings, depth and treatment area.

The number of sessions depends on the product, skin condition and desired result. Some treatments are performed as an initial series followed by maintenance, while others follow different schedules.

Some injectable skin treatments may be used around the eyes, but this is a delicate anatomical region. Product selection, depth and injection technique must be decided carefully. Manual injection may be preferred in certain patients.

Book a Skin Booster Assessment at LiV Clinic today

Interested in a skin booster but worried about pain, bruising or downtime?

A consultation with our professionally trained Doctors allows your skin to be assessed before a product or injection method is recommended.

At LiV Clinic, selected skin boosters may be administered using Dermashine Pro for controlled, automated microinjection or Manual techniques are also available when greater anatomical customisation is required.

Book your skin assessment at LiV Clinic to discover which skin booster—and which injection method—is most appropriate for your skin.